Most literate cities of 2008: NYC at #24, L.A. at #56
The "America's Most Literate Cities 2008" list has been released by Central Connecticut State University: link. Things like this generally fall into the FWIW/"for entertainment purposes only" category due to the varying definitions of "literate" and so forth. And, some sections of a given city are more "literate" than others, and some cities may be more cohesively "literate" vs certain others which only have a few islands of "literate-ness" scattered about.
Meanwhile, down at #26 comes New York City, being beaten out by, among others, Cincinnati, Pittsburgh, Cleveland, Raleigh, Columbus, Lexington-Fayette (Kentucky), Nashville-Davidson (Tennessee), Tulsa, and Oakland.